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On the show

Wayne Byrne

Operating Partner at Burnt Island Ventures

Serial water-tech founder behind four exits, the marquee being OxyMem (acquired by DuPont in 2019), now a board chair and Operating Partner at the water fund Burnt Island Ventures.

📍 Dublin, IrelandLinkedIn

Compiled by Antoine Walter - from insight gathered on and off his (don’t) Waste Water microphone!

Wayne Byrne is a Dublin-based serial water-tech entrepreneur who has moved to the other side of the table, sitting on water and climate-tech boards and working as an Operating Partner at Burnt Island Ventures. He is best known for co-founding and running OxyMem, the wastewater company DuPont acquired in 2019, one of the four exits he counts as of 2026.

On the show
1 interview
Marquee exit
OxyMem to DuPont
Based in
Dublin, Ireland
Today
Board chair & investor

Wayne Byrne did not set out to become a water investor, he got there by building and selling companies in the space for the better part of two decades. By his own account he has been involved in four successful exits over fifteen years, and the one that put him on the map is OxyMem, a spin-out of University College Dublin that he co-founded in 2013 and ran as chief executive. OxyMem commercialised something called a Membrane Aerated Biofilm Reactor, or MABR, which is a much more energy-efficient way of getting oxygen into the bugs that eat the pollution in wastewater, and it caught the eye of the chemicals giant DuPont, which took an early stake and then exercised its option to buy the company outright in December 2019.

Wayne Byrne is unusually candid about how that exit actually happened, because it was not a lucky phone call out of the blue. He spent nearly three years inside the university team before the technology was even spun out, so the whole thing was closer to a ten-year journey, and from the start he was, in his words, trying to begin with the end in mind and work out who the rightful owner of the technology would be if you imagined its future correctly. DuPont was on that shortlist for years, the acquisition was negotiated over a long period after their first investment through the Dow Ventures group, and so by the time the deal closed it was, as he puts it, a logical outcome rather than a left-field offer.

Wayne Byrne also turned the hard part of scaling deep tech into a second business. Across all those capital-intensive resource-efficiency companies he kept hitting the same wall: when you ask a water utility or an industrial customer to buy a first-of-a-kind technology, they have to carry the technical risk on their own balance sheet, and most of them simply will not. So he built Method Capital, a model that matches capital to high-technical-risk projects and shifts that risk onto the provider of the capital, letting the customer adopt new kit as if it were a service agreement rather than a nerve-wracking capital purchase. It is the same instinct that now has him chairing boards at companies like the ceramic-membrane firm Membrion and advising founders through fundraises and exits.

Wayne Byrne keeps one piece of hard-won advice close, and it is the kind of thing you only earn by living through a few near-disasters. He tells other entrepreneurs that sometimes your worst day can actually be your best day, because over the years he has noticed that the moments he found himself in a real jam were often exactly the moments a strange clarity arrived, and an opportunity came out of the mess that, with hindsight, turned into a positive outcome. There is a nice symmetry to where that instinct has led him, because back in 2021 on my (don’t) Waste Water microphone he pointed me towards a young water fund called Burnt Island Ventures as the one to watch, and a few years later he joined it himself.

“Sometimes your worst day can actually be your best day. Over the years, I found myself in plenty of jams or challenging situations, and within that time, an opportunity can come from that, which, with the benefit of hindsight, results in probably a positive outcome.”

Wayne Byrne is, in short, a builder who learned to be a backer: the rare operator who has carried a water technology all the way from a university lab to a corporate balance sheet, and now spends his days helping the next set of founders do the same. You can read more about how I track these companies and their funding in my Leviathan database and on the methodology behind it.

On (don’t) Waste Water

Wayne Byrne joined me on (don’t) Waste Water for a long conversation about his four exits and the bet on mercury-free UV disinfection:

The company

Typhon Treatment Systems
Typhon Treatment Systems is the company Wayne Byrne joined as CEO in 2021, and it is the focus of his (don’t) Waste Water interview. Typhon builds high-intensity UVC-LED reactors that disinfect drinking water and wastewater without the mercury vapour lamps the industry has relied on for a quarter of a century. Its pitch was to bridge the gap from small point-of-use systems all the way up to municipal scale, trading the higher energy cost of today's UVC-LEDs for real-time dose control and a mercury-free footprint ahead of the Minamata Convention phase-down.
Founded 2014 · United Kingdom

Frequently asked

Who is Wayne Byrne?
Wayne Byrne is a Dublin-based serial water-technology entrepreneur and investor. He co-founded and led OxyMem, a University College Dublin wastewater spin-out that DuPont acquired in 2019, counts four startup exits, and now chairs boards and works as an Operating Partner at the water fund Burnt Island Ventures.
What is OxyMem, and why did DuPont buy it?
OxyMem is the Irish company Wayne Byrne co-founded in 2013 to commercialise Membrane Aerated Biofilm Reactor technology, a far more energy-efficient way to aerate wastewater. DuPont took an early stake, then exercised its option to acquire OxyMem outright in December 2019, folding it into DuPont Water Solutions.
What does Method Capital do?
Method Capital is the firm Wayne Byrne founded to fix a problem he kept hitting: customers will not buy unproven deep tech if the technical risk sits on their balance sheet. Method Capital matches capital to high-risk projects and shifts the risk onto the capital provider, so the customer adopts new tech like a service.
What is Typhon Treatment Systems, the company in his episode?
Typhon Treatment Systems is the water-tech company Wayne Byrne joined as CEO in 2021, and the subject of his podcast interview. Typhon builds high-intensity UVC-LED reactors that disinfect water without mercury vapour lamps, aiming to scale the technology from point-of-use systems up to full municipal-grade treatment.
Is Wayne Byrne the same person as Burnt Island Ventures or OxyMem?
No. Wayne Byrne is a person, not a company. OxyMem is the wastewater startup he co-founded and sold to DuPont, and Burnt Island Ventures is the water-focused venture fund, founded by Tom Ferguson, where Wayne Byrne now works as an Operating Partner. Several unrelated people share his name.
Where can I listen to Wayne Byrne?
Wayne Byrne was a guest on the (don’t) Waste Water podcast in the episode "Four Successful Exits and Counting: What's next, disrupting UV Disinfection?". You can read the write-up, listen on the podcast player, or watch the conversation on YouTube using the links in the appearances section above.