Sreenath Bolisetty
Co-founder & CTO at BluAct Technologies
The ETH Zurich materials scientist who turned whey protein, the bodybuilder's supplement, into a low-energy water filter that strips heavy metals and even radioactive elements from water.
Compiled by Antoine Walter - from insight gathered on and off his (don't) Waste Water microphone! (as of June 2026)
Sreenath Bolisetty is the co-founder and CTO of BluAct Technologies, the 2016 ETH Zurich spin-off that purifies water with whey protein. His amyloid-carbon membranes, built from the same milk protein bodybuilders drink, cut heavy-metal ions by three to five orders of magnitude per pass and pull radioactive elements out at over 99.8% in one step (as of 2026).
Sreenath Bolisetty co-founded BluAct Technologies in 2016 to do something that sounds like a joke until you read the data: clean water with whey protein, the leftover from cheese-making that bodybuilders buy by the tub. During his years as a senior researcher at ETH Zurich, Bolisetty and his professor Raffaele Mezzenga found that if you denature that whey into amyloid protein fibrils, which are tiny self-assembled protein threads, and bind them to activated carbon, you get a membrane that grabs heavy-metal ions out of water and holds them. Their 2016 Nature Nanotechnology paper put a number on it: heavy-metal concentrations drop by three to five orders of magnitude on a single pass, and you can run it again and again.
Sreenath Bolisetty likes to call the material food-grade, because both halves of it, the whey protein and the activated carbon, are things you could eat, and the whole thing is manufactured wet, with no plastics. That matters for cost and for reach, because with a granulated version the filter runs on gravity alone, no electricity, which is exactly what you want in a place with bad water and no grid. And it is not picky about the poison. BluAct's membranes have pulled out heavy metals, pesticides and pharmaceuticals, precious metals like gold and platinum, and in a 2020 ETH study, radioactive elements from hospital effluent at over 99.8% in one filtration step, which put BluAct into talks about Fukushima.
Sreenath Bolisetty did not arrive at water by accident. He grew up in Nalgonda, a district in India that is well known for the wrong reason, fluoride in the groundwater, and he watched friends develop bone problems from drinking it. So when his lab work on recovering metal ions from mining waste showed him that the same protein fibrils could clean drinking water, the market math and the personal math pointed the same way. As he put it on the show, he realized he could find a meaningful career, because he grew up in a place where the water was not very safe to drink.
Sreenath Bolisetty has spent the years since taking the technology from the ETH lab into the field, running pilots across Europe, South America, Asia, the US and Australia, including a year-long study in Peru where, with the Swiss Embassy, BluAct tackled groundwater arsenic running about a hundred times over the safe limit. His ambition is deliberately un-flashy: one robust filter that an ordinary person, not a specialist engineer, can fit under a kitchen sink, doing the job that energy-hungry reverse osmosis (the high-pressure membrane filtering most bottled and desalinated water relies on) does today, but without the energy bill or the wasted water. It is the kind of unglamorous, deeply-technical water story I built my Leviathan database to keep track of.
“Our secret sauce is milk. Even the bodybuilders, when they want to build a body, they use this whey protein. We do some nanoengineering of this milk protein, and then these protein fibers are our active component, especially in the adsorption of heavy metal ions.”
On (don’t) Waste Water
The time Sreenath Bolisetty was a guest on the show:
The company
Frequently asked
- Who is Sreenath Bolisetty?
- Sreenath Bolisetty is a materials scientist and the co-founder and CTO of BluAct Technologies, a 2016 ETH Zurich spin-off in Switzerland. Originally from Nalgonda in India, he holds a PhD in physical chemistry and spent over a decade researching protein nanomaterials at ETH Zurich before commercializing them for water purification.
- What is BluAct Technologies and what does it do?
- BluAct Technologies is a Swiss water-purification company that Sreenath Bolisetty co-founded in 2016 as an ETH Zurich spin-off. It makes filters from whey-protein fibrils bonded to activated carbon that remove heavy metals, organic pollutants, precious metals, and even radioactive elements from drinking water and wastewater.
- How does whey protein purify water?
- Whey protein purifies water once it is denatured into amyloid fibrils, the approach Sreenath Bolisetty developed at ETH Zurich. Bonded to activated carbon, these fibrils adsorb heavy-metal ions, cutting their concentration by three to five orders of magnitude per pass, and also trap pesticides, pharmaceuticals and radioactive elements.
- Is BluAct Technologies an ETH Zurich spin-off?
- BluAct Technologies is an ETH Zurich spin-off, founded in 2016 by Sreenath Bolisetty on technology he co-invented with Professor Raffaele Mezzenga. The underlying patent was filed by ETH Zurich, and BluAct holds an exclusive license to it. The person is Bolisetty, the company is BluAct, the lab is Mezzenga's at ETH.
- Where can I listen to or watch the Sreenath Bolisetty episode?
- Sreenath Bolisetty appeared on (don't) Waste Water in episode S1E11, "Will this Bodybuilder's Secret Disrupt Water Treatment?", published in September 2020. You can watch it on YouTube or read the full write-up on dww.show, where he explains how a cheese by-product became a water filter.
